Islet and beta cell volumes in offspring of severely diabetic (ketotic) chinese hamsters

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Quantitative Assessment of Proliferative Effects of Oral Vanadium on Pancreatic Islet Volumes and Beta Cell Numbers of Diabetic Rats

Background: Oral vanadyl sulfate (vanadium) induces normoglycemia, proliferates beta cells and prevents pancreatic islet atrophy in streptozotocin-induced diabetic rats. Soteriological method is used to quantitate the proliferative effects of vanadium on beta-cell numbers and islet volumes of normal and diabetic rats. Methods: Adult male Sprague-Dawley rats were made diabetic with intravenous s...

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quantitative assessment of proliferative effects of oral vanadium on pancreatic islet volumes and beta cell numbers of diabetic rats

background: oral vanadyl sulfate (vanadium) induces normoglycemia, proliferates beta cells and prevents pancreatic islet atrophy in streptozotocin-induced diabetic rats. soteriological method is used to quantitate the proliferative effects of vanadium on beta-cell numbers and islet volumes of normal and diabetic rats. methods: adult male sprague-dawley rats were made diabetic with intravenous s...

متن کامل

Quantitative Assessment of Proliferative Effects of Oral Vanadium on Pancreatic Islet Volumes and Beta Cell Numbers of Diabetic Rats.

BACKGROUND Oral vanadyl sulfate (vanadium) induces normoglycemia, proliferates beta cells and prevents pancreatic islet atrophy in streptozotocin-induced diabetic rats. Soteriological method is used to quantitate the proliferative effects of vanadium on beta-cell numbers and islet volumes of normal and diabetic rats. METHODS Adult male Sprague-Dawley rats were made diabetic with intravenous s...

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Observation of Retinopathy in Metahypophyseal Diabetic Chinese Hamsters.

GConsidering the extensive use of experimental animals in diabetic research, the paucity of reports on retinal lesions in diabetic animals is striking. In a 1961 review on diabetes in animals, Meier does not list retinopathy in his pathologic survey. More recently, however, Patz and Maumenee have reported retinopathy in a spontaneously diabetic dog, and Hausler, Sibay, and Campbell have describ...

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HISTOLOGICAL AND IMMUNOHISTOCHEMICAL STUDY OF PANCREATIC ISLET BETA CELLS OF DIABETIC RATS TREATED WITH ORAL VANADYL SULPHATE

Vanadium salts have been suggested as a possible therapeutic agent for the treatment of diabetes. The aim of the present study was to clarify histological and immunohistochemical changes that occur in the pancreatic beta (β) cells of vanadyl sulphate (VS)-treated streptozotocin (STZ) induced diabetic rats. Male Wi star rats were made diabetic by injecting a single intravenous dose of STZ (...

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ژورنال

عنوان ژورنال: Diabetologia

سال: 1970

ISSN: 0012-186X,1432-0428

DOI: 10.1007/bf01212225